Cytosorbents Corporation
CROSSLINKED POLYSACCHARIDE BASED ABSORBENTS FOR REMOVAL OF ANTI-A AND/OR ANTI-B ANTIBODIES FROM HUMAN PLASMA AND WHOLE BLOOD

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Abstract:

The invention concerns polymeric media based on modified natural polysaccharides for removing one or both of Anti-A Antibodies and Anti-B Antibodies from human blood or plasma, the media comprising one or both of (i) a polymeric solid support with a blood group A Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions, and (ii) a polymeric solid support with a blood group B Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions.

Status:
Application
Type:

Utility

Filling date:

2 Dec 2019

Issue date:

3 Feb 2022