Cytosorbents Corporation
CROSSLINKED POLYSACCHARIDE BASED ABSORBENTS FOR REMOVAL OF ANTI-A AND/OR ANTI-B ANTIBODIES FROM HUMAN PLASMA AND WHOLE BLOOD
Last updated:
Abstract:
The invention concerns polymeric media based on modified natural polysaccharides for removing one or both of Anti-A Antibodies and Anti-B Antibodies from human blood or plasma, the media comprising one or both of (i) a polymeric solid support with a blood group A Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions, and (ii) a polymeric solid support with a blood group B Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions.
Status:
Application
Type:
Utility
Filling date:
2 Dec 2019
Issue date:
3 Feb 2022