Cue Biopharma, Inc.
Antigen-Presenting Polypeptides with Chemical Conjugation Sites and Methods of Use Thereof
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Abstract:
The present disclosure provides antigen-presenting polypeptides, including single-chain antigen-presenting polypeptides and multimeric antigen-presenting polypeptides comprising one or more chemical conjugation sites for incorporation of, for example, epitope containing polypeptides. The single-chain and multi-chain antigen-presenting polypeptides and their epitope conjugates are useful for modulating the activity of a T-cell, and accordingly, the present disclosure provides methods of modulating activity of a T-cell in vitro and in vivo as methods of treatment.
Status:
Application
Type:
Utility
Filling date:
7 Sep 2021
Issue date:
5 May 2022