Cyclerion Therapeutics, Inc.
DEUTERATED sGC STIMULATORS

Abstract:

This invention relates to deuterated compounds of Formula I, and pharmaceutically acceptable salts thereof. ##STR00001## or a pharmaceutically acceptable salt thereof, wherein each of Y.sup.1, Y.sup.2, Y.sup.3, Y.sup.4, Y.sup.5a, Y.sup.5b, Y.sup.6, Y.sup.7, Y.sup.8, Y.sup.9, Y.sup.10, Y.sup.11a and Y.sup.11b is independently selected from hydrogen and deuterium, as well as pharmaceutical compositions, methods and uses thereof.