Warner Bros. Discovery, Inc.
Thienopyrazine carboxamides as ubiquitin-specific protease inhibitors

Abstract:

The disclosure relates to inhibitors of USP28 and/or USP25 useful in the treatment of cancers, inflammation, autoimmune diseases, and infectious diseases, having the Formula: (I), where R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.4', R.sub.5, R.sub.6, X, and n are described herein. ##STR00001##