Warner Bros. Discovery, Inc.
[6,6] fused bicyclic HDAC8 inhibitors

Abstract:

The present invention is directed to compounds of Formula I: ##STR00001## and pharmaceutically acceptable salts thereof, wherein R.sub.1, R.sub.2, R.sub.2', L, X, W, Y.sup.1, Y.sup.2, Y.sup.3, and Y.sup.4 are described herein, useful as inhibitors of zinc-dependent histone deacetylases (HDACs) and in the treatment of diseases or disorders associated with HDACs.