Warner Bros. Discovery, Inc.
QUINAZOLINONES AND AZAQUINAZOLINONES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS

Abstract:

The present disclosure relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula: ##STR00001## where R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.4', X.sub.1, Y.sub.1, Y.sub.2, Y.sub.3, Y.sub.4, n, and m are described herein.