Denali Therapeutics Inc.
Fusion proteins comprising enzyme replacement therapy enzymes

Last updated:

Abstract:

Provided herein are fusion proteins that comprise an enzyme replacement therapy enzyme and an Fc region, as well as methods of using such proteins to treat a lysosomal storage disorder. Methods for transporting agents across the blood-brain barrier are also provided herein.

Status:
Grant
Type:

Utility

Filling date:

15 Mar 2019

Issue date:

22 Dec 2020