Denali Therapeutics Inc.
Fusion proteins comprising enzyme replacement therapy enzymes
Last updated:
Abstract:
Provided herein are fusion proteins that comprise an enzyme replacement therapy enzyme and an Fc region, as well as methods of using such proteins to treat a lysosomal storage disorder. Methods for transporting agents across the blood-brain barrier are also provided herein.
Status:
Grant
Type:
Utility
Filling date:
15 Mar 2019
Issue date:
22 Dec 2020