Corning Incorporated
SYNTHESIS OF BRANCHED ALKYL ALCOHOLS BY CU(I)-CATALYZED C-C COUPLING BETWEEN ALKYL GRIGNARD REAGENTS AND ALKYL TOSYLATES

Abstract:

A method includes: providing a mixture including at least one alkyl tosylate and a Grignard reagent; and reacting the at least one alkyl tosylate with the Grignard reagent in a C--C coupling reaction mechanism to form a branched aliphatic alcohol.