Corning Incorporated
METHODS FOR DETERMINING CHEMICAL HETEROGENEITY OF GLASS CONTAINERS

Abstract:

A method of making a glass container for storing a pharmaceutical formulation includes heating a Type 1 glass composition according to ASTM Standard E438-92 (2011) to form a glass melt, and forming the glass melt into a glass tube. The glass tube is then re-formed into the glass container having a glass body with: a wall region with an interior surface and an exterior surface; a heel region; and a base region. The interior surface of the glass container is formed by the interior surface of the glass body. A glass pharmaceutical container has a CDR value of less than or equal to 6.0, at least a class A2 base resistance or better according to ISO 695, at least a type HGB2 hydrolytic resistance or better according to ISO 719, and Type 1 chemical durability according to USP <660>.