Genocea Biosciences, Inc.
TREATMENT METHODS

Abstract:

Methods and compositions for identifying tumor antigens of human lymphocytes, and for identifying subjects for cancer therapy, are provided herein. In some embodiments, the method comprises administering to the subject an immunogenic composition comprising one or more selected stimulatory antigens (e.g., one or more stimulatory antigens described herein) or immunogenic fragments thereof, wherein the immunogenic composition is administered according to a dosing regimen comprising an initial dose of the immunogenic composition and additional doses of the immunogenic composition, wherein after an initial dose is administered, an additional dose is administered 3 weeks following the initial dose, an additional dose is administered 6 weeks following the initial dose, an additional dose is administered 12 weeks following the initial dose, and an additional dose is administered 24 weeks following the initial dose.