G1 Therapeutics, Inc.
Substituted dihydropyrazino[1 ',2':1,5]pyrrolo[2,3-d]pyrimidine-based antiproliferative agents

Abstract:

This invention is in the area of pyrimidine-based compounds for the treatment of disorders involving abnormal cellular proliferation, including but not limited to tumors and cancers. Representative examples of compounds of the present invention include ##STR00001##