G1 Therapeutics, Inc.
MORPHIC FORMS OF TRILACICLIB AND METHODS OF MANUFACTURE THEREOF

Abstract:

An advantageous isolated morphic form of trilaciclib which is 2'-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)-7',8'-dihydro-6'H-spir- o[cyclohexane-1,9'-pyrazino[1',2':1, 5]pyrrolo[2,3 -d]pyrimidin]-6'-one, for example in the form of a di-hydrochloride salt or a dihydrochloride, dihydrate.