Hologic, Inc.
Breast phantom with encapsulated hydrogel

Abstract:

Methods and devices for testing effects of external stimuli on breast appearance in an x-ray image are provided. A model for testing may include a breast phantom with an encapsulated hydrogel. In some examples, a three-dimensional cell culture and/or microfluidic channels may be encapsulated in the hydrogel. A first set of x-ray images of the model may be captured, thermal energy may be applied to the model, and a second set of x-ray images of the model may be captured while the thermal energy is being applied for comparison with the first set to determine effects of the thermal energy on appearance of the model. By incrementally increasing an amount of thermal energy applied and capturing subsequent x-ray images for comparison, an appropriate temperature range may be determined for heating compression surfaces of a breast imaging system to reduce compression-related pain and discomfort for patients without compromising x-ray image quality.