International Business Machines Corporation
BIOMARKER SELECTION AND MODELING FOR TARGETED MICROBIOMIC TESTING

Abstract:

A system, method, and computer program product that includes a computer readable storage medium with program instructions, executable by a processer, to cause a device to perform the method. The method includes receiving a set of biomarkers associated with a known phenotype, generating at least one ranking for each biomarker based on a feature selection method, selecting a set of potential key biomarkers from the set of biomarkers based on the ranking, and selecting a set of key biomarkers from the potential key biomarkers. The method also includes building a model for phenotype prediction based on the set of key biomarkers.