IDEAYA Biosciences, Inc.
METHODS OF INHIBITING PROLIFERATIVE CELLS
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Abstract:
The present invention provides methods of negatively modulating the Werner protein (WRN) to inhibit proliferative cells characterized by high microsatellite instability (MSI-H), for example to treat proliferative diseases (such as cancer) characterized by high MSI (MSI-H). Further provided are compositions used in such methods.
Status:
Application
Type:
Utility
Filling date:
17 Jun 2019
Issue date:
2 Dec 2021