Illumina, Inc.
PREPARATION OF DNA SEQUENCING LIBRARIES FOR DETECTION OF DNA PATHOGENS IN PLASMA

Abstract:

The application provides an agnostic, shotgun nucleic acid sequencing-based method for the detection of pathogens in samples from human patients, animals, or plants. The method includes dehosting the sample of the nucleic acid molecules of host origin and provides for the detection of pathogens without prior knowledge of their genome sequences.