Illumina, Inc.
Predicting Sequencer Subsystem Instability in Sequencing Systems

Abstract:

The technology disclosed relates to detecting malfunction in a sequencer. In particular, the technology disclosed relates to receiving sensor data obtained from a sensor of the sequencer, applying a smoothing function to the sensor data to produce a smoothed time series, determining changes between smoothed successive datum in the smoothed time series that exceed a predetermined change, determining a degree of instability based upon the predetermined change, and generating an alert indicating that the sequencer is malfunctioning when the degree of instability exceeds a predetermined threshold.