Illumina, Inc.
METHODS FOR DETERMINING SUB-GENIC COPY NUMBERS OF A TARGET GENE WITH CLOSE HOMOLOGS USING BEADARRAY

Abstract:

Presented herein are methods and compositions for copy number estimation of a target gene with close homologs, comprising determining sub-genic copy numbers. The methods are useful for estimating copy numbers of clinically important genes with high sequence similarity between gene of interest and their homologs, including non-functional pseudogenes.