Illumina, Inc.
COMPOSITIONS AND METHODS FOR MAKING CONTROLS FOR SEQUENCE-BASED GENETIC TESTING

Abstract:

Provided herein are compositions that include nucleic acid fragments produced from double-stranded template nucleic acids, such as cell free DNA. The compositions can be used as positive or negative controls for quality of library preparation methods, calibration of an instrument such as a sequencing instrument, and/or a validation for a nucleic acid sequencing test. Also provided are methods for making the nucleic acid fragments.