ImmunoGen, Inc.
Methods for preparing substituted 12a,13-dihydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-6-ones

Abstract:

The invention provides novel methods for preparing indolinobenzodiazepine monomer compounds and their synthetic precursors. In an embodiment, the method discloses preparation of a compound represented by formula (III): ##STR00001##