ImmunoGen, Inc.
METHODS FOR ANTIBODY DRUG CONJUGATION, PURIFICATION, AND FORMULATION

Abstract:

Methods of producing, purifying, and formulating antibody drug conjugates (ADCs) are provided herein. The methods use continuous conjugation processes, single-pass tangential flow filtration, countercurrent diafiltration, and/or in-line process automation technologies. The methods decrease process times and costs and improve product consistency.