Inovio Pharmaceuticals, Inc.
TUMOR-SPECIFIC NEOANTIGENS AND METHODS OF USING THE SAME

Abstract:

The disclosure relates to methods of manufacturing individualized vaccines that comprise nucleic acid molecules that encode one or more neoantigens specific for antigens that are expressed by a tumor in a subject. Compositions comprising coding regions encoding neoantigens organized in a pattern of nucleic acid sequences are also disclosed as well as methods of immunizing a subject using the same.