Ionis Pharmaceuticals, Inc.
COMPOUNDS AND METHODS FOR MODULATING TMPRSS6 EXPRESSION

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Abstract:

Disclosed herein are compositions and compounds comprising modified oligonucleotides for modulating TMPRSS6 and modulating an iron accumulation disease, disorder and/or condition in an individual in need thereof. Iron accumulation diseases in an individual such as polycythemia, hemochromatosis or .beta.-thalassemia can be treated, ameliorated, delayed or prevented with the administration of antisense compounds targeted to TMPRSS6.

Status:
Application
Type:

Utility

Filling date:

24 Sep 2021

Issue date:

18 Aug 2022