Kronos Bio, Inc.
CRYSTALLINE MONOMESYLATE SALT OF 6-(6-AMINOPYRAZIN-2-YL)-N-(4-(4-(OXETAN-3-YL)PIPERAZIN-1-YL)PHENYL)IMIDAZ- O[1,2-a]PYRAZIN-8-AMINE

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Abstract:

The present disclosure relates to compounds that are Syk inhibitors or pharmaceutically acceptable salts or co-crystals thereof, and pharmaceutical compositions thereof, and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, a Syk inhibitor is a crystalline monomesylate salt of 6-(6-aminopyrazin-2-yl)-N-(4-(4-(oxetan-3-yl)piperazin-1-yl)pheny- l)imidazo-[1,2-a]pyrazin-8-amine of formula 2: ##STR00001##

Status:
Application
Type:

Utility

Filling date:

28 Oct 2020

Issue date:

4 Mar 2021