Laboratory Corporation of America Holdings
Methods and Systems to Measure Cannabidiol (CBD)

Abstract:

Disclosed are methods, systems and computer-program products to measure cannabidiol (CBD) and/or its metabolites in a biological sample. The methods and systems may include LC-MS/MS. For example the method may include obtaining MS/MS data comprising a predetermined MS/MS transition for THC and/or at least one THC metabolite and CBD and/or at least one CBD metabolite, and determining a ratio of the amount of the CBD and/or at least one CBD metabolite to the amount of the THC and/or at least one THC metabolite for the biological sample. In certain embodiments, the methods and/or systems are used to distinguish CBD from THC use in a subject.