Eli Lilly and Company
IgG Bispecific Antibodies and Processes for Preparation

Abstract:

The present invention provides fully IgG bi-specific antibodies comprising designed residues in the interface of the heavy chain-heavy chain (C.sub.H3/C.sub.H3) domains, processes for preparing said fully IgG bi-specific antibodies, and nucleic acids, vectors and host cells encoding the same.