Eli Lilly and Company
RECOMBINANTLY ENGINEERED, LIPASE/ESTERASE-DEFICIENT MAMMALIAN CELL LINES
Last updated:
Abstract:
Mammalian cell lines with reduced expression and/or activity of lipases/esterases, and methods of producing the same are provided. Also provided are compositions comprising polysorbate and recombinant proteins produced in said mammalian cells which have improved polysorbate stability.
Status:
Application
Type:
Utility
Filling date:
14 Apr 2022
Issue date:
11 Aug 2022