Eli Lilly and Company
METHOD AND SYSTEM FOR DETERMINING GLUCOSE CHANGE IN A SUBJECT

Abstract:

There is provided a method and a system for determining glucose change in a subject, which includes receiving subject model parameters. The subject model parameters of a state-based model of the subject may have been estimated based on: actual glucose measurements and past subject model parameters. An innovation parameter and an innovation covariance parameter are determined using a Kalman filter based on the subject model parameters and a previous state of the subject. A test statistic is calculated based on the determined innovation parameter and the innovation covariance parameter. The calculated test statistic is compared to a given threshold. In response to the calculated test statistic being above the given threshold, an indication of the glucose change is outputted.