Magenta Therapeutics, Inc.
METHODS OF TREATING CANCER WITH ARYL HYDROCARBON RECEPTOR ANTAGONISTS

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Abstract:

The disclosure relates to aryl hydrocarbon receptor antagonists, such as substituted imidazopyridines and imidazopyrazines, as well as methods of modulating aryl hydrocarbon receptor activity and treating various pathologies, such as cancer, by administration of these aryl hydrocarbon receptor antagonists. Additionally, the disclosure provides methods of synthesizing aryl hydrocarbon receptor antagonists, such as substituted imidazopyridines and imidazopyrazines, as well as compositions and kits containing aryl hydrocarbon receptor antagonists that can be used for the treatment of diseases and disorders.

Status:
Application
Type:

Utility

Filling date:

17 Oct 2019

Issue date:

9 Dec 2021