MannKind Corporation
FORMATION OF N-PROTECTED 3,6-BIS-(4-AMINOBUTYL)-2,5-DIKETOPIPERAZINE THROUGH A CYCLIC ALPHA-N-PROTECTED AMINO ESTER
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Abstract:
A method for the synthesis of N-protected 3,6-aminoalkyl-2,5-diketopiperazines is provided. The method includes obtaining a cyclic .alpha.-N protected active amino ester and adding it to a mixture of an amine catalyst in an organic solvent.
Status:
Application
Type:
Utility
Filling date:
2 Mar 2020
Issue date:
25 Jun 2020