MannKind Corporation
Formation of N-protected 3,6-bis-(4-aminobutyl)-2,5-diketopiperazine through a cyclic .alpha.-N-protected amino ester

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Abstract:

A method for the synthesis of N-protected 3,6-aminoalkyl-2,5-diketopiperazines is provided. The method includes obtaining a cyclic .alpha.-N protected active amino ester and adding it to a mixture of an amine catalyst in an organic solvent.

Status:
Grant
Type:

Utility

Filling date:

2 Mar 2020

Issue date:

22 Dec 2020