NuCana plc
Combination Therapy

Abstract:

This invention relates to a combination of 2'-Deoxy-2',2'-difluoro-D-cytidine-5'-O-[phenyl (benzoxy-L-alaninyl)] phosphate) (NUC-1031) and carboplatin, or other forms of platinum, and the use of the combination in treating cancer patients selected based on the patient's cancer's response to platinum. In particular the invention concerns the treatment of patients that have platinum sensitive cancers or platinum partially sensitive cancers.