NuCana plc
FORMULATION COMPRISING A GEMCITABINE-PRODRUG
Last updated:
Abstract:
This invention relates to pharmaceutical formulations of gemcitabine-[phenyl-benzoxy-L-alaninyl)]-phosphate, a monophosphate derivative of the well-known oncology drug gemcitabine. In particular, the invention relates to formulations which comprise a polar aprotic solvent, preferably dimethyl acetamide (DMA). Formulations comprising these solvent provide therapeutically effective treatments of gemcitabine-[phenyl-benzoxy-L-alaninyl)]-phosphate. The invention also relates to methods of using said formulations and kits comprising said formulations.
Status:
Application
Type:
Utility
Filling date:
19 May 2021
Issue date:
3 Feb 2022