NuCana plc
Synthesis of phosphate derivatives

Last updated:

Abstract:

The present invention is a process for the preparation of certain 5'-phosphoramidate nucleotide diastereoisomers. The phosphoramidates include those useful in the treatment of cancer such as NUC-3373 (5-fluoro-2'-deoxyuridine-5'-O-[1-naphthyl(benzyloxy-L-alaninyl)]phosphat- e).

Status:
Grant
Type:

Utility

Filling date:

14 Jun 2018

Issue date:

16 Aug 2022