Nektar Therapeutics
Morphinan derivatives for the treatment of neuropathic pain

Abstract:

The present invention relates to compounds and their use as ligands for mu opioid receptors. Also included are methods for preparing the compounds and pharmaceutical compositions containing the compounds. In one or more embodiments of the invention, a compound according to Formula I is provided: and pharmaceutically acceptable salts thereof, wherein R.sup.1-R.sup.11 are as described herein. ##STR00001##