Natera, Inc.
Systems and Methods for Detection of Aneuploidy
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Abstract:
Provided herein are improved methods for detecting aneuploidy in a sample. The methods in certain embodiments are used for the analysis of circulating DNA in serum samples, such as circulating fetal DNA or circulating tumor DNA. In certain embodiments, chromosome or chromosome segments of interest are used to set a bias model and/or a control value for a z-score determination, in illustrative examples without the use of a control chromosome.
Status:
Application
Type:
Utility
Filling date:
2 Sep 2021
Issue date:
23 Dec 2021