Natera, Inc.
IMPROVED LIQUID BIOPSY USING SIZE SELECTION

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Abstract:

Provided herein are improved methods of determining the sequences of cell-free DNA (cfDNA). The methods in certain embodiments are used for the analysis of circulating DNA in serum samples, such as circulating fetal DNA, circulating donor derived DNA, or circulating tumor DNA. In certain embodiments, the methods include selectively enriching trinucleosomal, dinucleosomal, mononucleosomal or sub-mononucleosomal DNA from the isolated cfDNA.

Status:
Application
Type:

Utility

Filling date:

14 Apr 2020

Issue date:

19 May 2022