Natera, Inc.
METHODS FOR DETECTING IMMUNE CELL DNA AND MONITORING IMMUNE SYSTEM
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Abstract:
The disclosure herein provides methods and compositions for detecting or monitoring immune cell populations in biological samples. The methods and compositions disclosed herein are particularly useful for detecting or monitoring immune cell populations in patients suffering from a disease or undergoing treatment of a disease resulting in depletion of immune cells. In particular, the present disclosure provides method for using multiplex PCR combined with next-generation DNA sequencing to detect DNA containing recombined V(D)J gene segments which can be used to detect immune cells.
Status:
Application
Type:
Utility
Filling date:
29 May 2020
Issue date:
11 Aug 2022