Novartis AG
COMBINATIONS COMPRISING TROPIFEXOR AND CENICRIVIROC

Abstract:

The invention provides a pharmaceutical combination comprising 2-[(1R,3r,5S)-3-({5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol- -4-yl}methoxy)-8-azabicyclo [3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid or a stereoisomer, enantiomer, pharmaceutically acceptable salt, prodrug, ester thereof or amino acid conjugate thereof; and cenicriviroc or a pharmaceutically acceptable salt, solvate, prodrug or ester thereof; for use in treating or preventing a liver disease or disorder.