Novartis AG
COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN DEGRADATION
Last updated:
Abstract:
The invention provides compositions including a fusion polypeptide and methods for making a fusion polypeptide that includes a COF1/CRBN-binding polypeptide, COF2/CRBN-binding polypeptide, or COF3/CRBN-binding polypeptide and a heterologous polypeptide of interest.
Status:
Application
Type:
Utility
Filling date:
18 Oct 2018
Issue date:
29 Oct 2020