Pfizer Inc.
POLYMORPH FORM OF A MONOPHOSPHATE HYDRATE SALT OF A KNOWN TETRAHYDROISOQUINOLINE DERIVATIVE

Abstract:

This invention relates to crystalline (1S,2S,3S,5R)-3-((6-(difluoromethyl)-5-fluoro-1,2,3,4-tetrahydroisoquinol- in-8-yl)oxy)-5-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-- diol monophosphate hydrate, and to compositions and therapeutic uses thereof.