Pfizer Inc.
Anti-proliferative agents for treating PAH

Abstract:

This invention relates to compounds of general Formula I ##STR00001## in which A, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined herein, and the pharmaceutically acceptable salts thereof; to pharmaceutical compositions comprising such compounds and salts; to methods of using such compounds, salts and compositions for treating pulmonary hypertension and related diseases, like pulmonary arterial hypertension; to methods of using such compounds, salts and compositions for treating abnormal cell growth, such as cancer; and to processes to make such compounds, salts and compositions.