Pfizer Inc.
AMINOPYRIMIDINYL DERIVATIVES

Abstract:

A compound of formula I: ##STR00001## or a pharmaceutically acceptable salt thereof, wherein R.sup.1 and R.sup.2 are each independently hydrogen or hydroxy; wherein R.sup.1 and R.sup.2 are not both hydroxy. Also provided are methods of treatment as Janus Kinase inhibitors and pharmaceutical compositions containing the compounds of the invention and combinations thereof with other therapeutic agents.