Pliant Therapeutics, Inc.
Amino acid compounds and methods of use

Abstract:

The invention relates to compounds of formula (I): formula (I) or a salt thereof wherein R.sup.1, R.sup.5, R.sup.7, R.sup.8, X, m, n, p and q are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are .alpha.v.beta.6 integrin inhibitors that are useful for treating tissue specific fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP). ##STR00001##