Pliant Therapeutics, Inc.
AMINO ACID COMPOUNDS WITH UNBRANCHED LINKERS AND METHODS OF USE

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Abstract:

The invention relates to compounds of formula (A): ##STR00001## or a salt thereof, wherein R.sup.1, R.sup.2, R.sup.5a, R.sup.5b, R.sup.6a, R.sup.6b, R.sup.7a, R.sup.7b, R.sup.8a, R.sup.8b, R.sup.9a, R.sup.9b, R.sup.10a, R.sup.10b, R.sup.11a, R.sup.11b, R.sup.21, n, and G are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are .alpha..sub.V.beta..sub.6 integrin inhibitors that are useful for treating fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

Status:
Application
Type:

Utility

Filling date:

27 Jun 2019

Issue date:

23 Apr 2020