Praxis Precision Medicines, Inc.
Compounds and their methods of use

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Abstract:

The present invention is directed to, in part, fused heteroaryl compounds and compositions useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including neurological disorders (e.g., Dravet syndrome, epilepsy), pain, and neuromuscular disorders are also provided herein.

Status:
Grant
Type:

Utility

Filling date:

15 Aug 2018

Issue date:

22 Mar 2022