Prelude Therapeutics Incorporated
SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5)

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Abstract:

The disclosure is directed to compounds of Formula I, Formula II, Formula III, Formula IV, Formula V, or Formula VI: Methods of their use in inhibiting a protein arginine methyltransferase 5 (PRMT5) enzyme and treating disease, as well as methods of their preparation are also described. ##STR00001## ##STR00002##

Status:
Application
Type:

Utility

Filling date:

20 Feb 2018

Issue date:

6 May 2021