Quantum-Si incorporated
SYSTEMS AND METHODS FOR DETERMINING QUANTITATIVE LOADING OF AN INTEGRATED DEVICE

Abstract:

Aspects of the disclosure relate to techniques for determining a measure of quantitative loading of a sample in an integrated device. According to some embodiments, there is provided a method for determining a measure of quantitative loading of a sample in an integrated device, the method comprising exciting, with excitation light from at least one excitation source, one or more reference dye molecules that, during the exciting with the excitation light, are attached to respective biomolecules of the sample bound to a surface of a chamber of one or more chambers of the integrated device, obtaining a signal emitted by the one or more reference dye molecules in response to the excitation light, and determining, based on the signal emitted by the one or more reference dye molecules, the measure of quantitative loading of the sample.