Arcus Biosciences, Inc.
Inhibitors of CD73-mediated immunosuppression

Last updated:

Abstract:

Compounds that modulate the conversion of AMP to adenosine by 5'-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5'-nucleotidase, ecto is also provided.

Status:
Grant
Type:

Utility

Filling date:

17 Nov 2017

Issue date:

8 Mar 2022