Regeneron Pharmaceuticals, Inc.
ACTIVIN A ANTIBODY FORMULATIONS AND METHODS OF USE THEREOF

Abstract:

The present invention provides novel pharmaceutical formulations comprising an antibody that specifically binds to human Activin A. The formulations may contain, in addition to an anti-Activin A antibody, a histidine buffer, an organic cosolvent, and a thermal stabilizer. The pharmaceutical formulations of the present invention exhibit a surprising degree of antibody stability after storage for several months and after being subjected to thermal and other physical stress.